We report net peptide content, not just purity — so the milligrams you dose aren't padded with water and counter-ion. RP-HPLC purity and ESI-MS identity, on a lot-numbered COA.
Net peptide content, not just purity — RP-HPLC + ESI-MS, lot-numbered COA.
Net peptide content on every lot's COA.
Reading a Peptide HPLC Trace — A 5-Minute Field Guide for Bench Scientists. Read our briefing →
Reading a peptide HPLC trace — a field guide. Read →
On reading HPLC traces. Read →
About
Headquartered in Shanghai, China, Lyochem synthesises, characterises, documents, and ships sequence-verified research peptides under one quality system. Our buyers are academic laboratories, biotech R&D groups, contract research organisations (CROs), pharmaceutical R&D departments, and shared instrumentation cores across multiple regions.
Stability
A reference standard earns its place by giving the same answer this month and next year — and in the lab replicating your work. We lyophilise to a defined, stable cake, hold residual moisture to the Karl Fischer specification, and back the re-test dating with a 12-month −20 °C stability series rather than an assumed shelf life. The lot you cite in a methods section behaves the same on every bench.
Water content held to the Karl Fischer specification on every lot.
Re-test dating backed by a documented study, not an assumed shelf life.
Sequence-verified and HPLC / MS characterised, so successive lots hold in a protocol.
A defined solid that dissolves the same way on every bench.
How we're organized
Lyochem is structured so every buyer-facing decision, pricing, lead time, COA, regulatory review, passes through people who own the relevant function. Inquiries land with sales, but quality and regulatory review every quote before it goes out.
Function
Oversees synthesis, purification, lyophilization, vial filling, and packaging across all production lines. Final sign-off on production schedules and shop-floor changes.
Tenure
10–15 years in synthetic peptide manufacturing
Background
Solid-phase peptide synthesis at a major Chinese CDMO; pharma-API process development for both research-grade and pharmacy-grade material.
Function
Owns analytical methods, stability program, batch release, and COA approval workflow. No batch ships without QA sign-off on the analytical packet.
Tenure
8–12 years in pharmaceutical QA
Background
Documented analytical method development (HPLC, mass spec, Karl Fischer, LAL endotoxin); USP/EP/CP method references where applicable.
Function
Sequence design, non-standard modifications (PEG conjugation, lipidation, copper coordination, D-amino-acid incorporation, intramolecular disulfide bridging), pilot-scale process development.
Tenure
12+ years in synthetic peptide R&D
Background
Doctoral-level training in peptide chemistry; prior experience with custom-sequence synthesis for both research and clinical-development programs.
Function
Direct contact for research-buyer accounts worldwide. Reviews each inquiry for research-institution fit and destination-market eligibility before pricing; written advisory on RUO scope, end-user verification, and cross-border research-reagent import frameworks.
Tenure
8–10 years in research-reagent B2B sales + regulatory
Background
Cross-border research-peptide commercial relationships with academic, biotech R&D, CRO, and pharma R&D buyers; tracking of cross-jurisdictional research-reagent import frameworks across the US, EU, UK, and APAC.
Individual leader identities are disclosed under NDA at the commercial-relationship stage rather than on the public site. Avatars above are monogram-style identifiers, not photographs, they represent the function, not a specific person.
How we work
The manufacturing behind Lyochem has run since 2013 — a peptide-synthesis operation that began supplying research-grade material to academic labs and CROs and grew into an end-to-end peptide research-standards atelier covering synthesis, chromatography purification, lyophilisation, vial filling, and characterisation under a single quality system.
Today the same facility releases sequence-verified reference standards for academic laboratories, biotech R&D groups, CROs, pharmaceutical R&D departments, and shared instrumentation cores across multiple regions — strictly Research Use Only.
Our positioning is deliberately not the cheapest in the market. We invest in documentation (batch-specific COA, HPLC + Mass Spec, sequence verification by LC-MS/MS, 12-month −20 °C stability series) and in research-institution qualification — every quote is reviewed for research-buyer fit before pricing.
The atelier's analytical methods are aligned with USP <621> (HPLC), USP <1225> (analytical validation), ICH Q2, and EP equivalents — the same method-provenance language the lot reports cite, so the documentation reads like a published methods section rather than a marketing badge row.
First reply under 24 hours from a synthesis chemist or analytical contact — not a templated auto-response. Lot-specific HPLC chromatogram, ESI-MS identity, MS/MS sequence (on request), KF water, and stability data returned with the quote.