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Thymic immune-modulation peptide(s)
Research documentation
Ask sales for the Thymalin/Thymulin batch COA and the analytical evidence needed to qualify the material for your study. Confirm the available purity and identity records, lot continuity, handling information, and method requirements before ordering.
Overview
Thymalin and Thymulin are distinct thymus-derived immune-modulating products routinely conflated by buyers, largely because of a shared thymic-origin etymology and overlapping marketed indications. Thymulin (Serum Thymic Factor, FTS) is a single, defined 9-amino-acid zinc-binding peptide, CAS 63958-90-7. Thymalin is something else entirely: a multi-component peptide extract of bovine thymus tissue associated with the Khavinson research program and regulated status in Russia and parts of Eastern Europe, characterized by a compositional fingerprint rather than one molecule. The two are neither chemically equivalent nor interchangeable in research or clinical protocols. Lyochem lists both materials — the defined zinc-binding nonapeptide Thymulin and the bovine-thymus extract Thymalin — under this SKU, and the desired form must be specified at order placement. The applicable batch COA states unambiguously whether what ships is the single-molecule Thymulin peptide or the multi-component extract that is Thymalin; buyers should confirm identity on the COA before use rather than infer it from catalog wording.
Applications & buyer fit
Buyers in this category are research labs studying immune-modulation, cytokine signalling, and antimicrobial activity. The defining QC requirement is bacterial-endotoxin control: many downstream assays (NF-κB reporters, macrophage-activation panels, neutrophil-priming readouts) are themselves activated by endotoxin contamination, so a clean LAL on the specific lot is a precondition rather than a nice-to-have. LL-37 and related cationic antimicrobial peptides additionally benefit from low-bind plasticware during dilution.
Academic Laboratories
Universities, medical schools, and government research institutes qualifying a reference standard for a method-development or in vivo workflow.
Every lot has its own batch-specific CoA — HPLC purity and MS identity, plus any analytical scope agreed at quote stage — tied to the exact lot you receive.
Review a representative batch CoA before you order, so you can confirm the packet matches what your method or sponsor audit needs.
Supplied strictly as a research reagent to research institutions — not a finished dosage form and not for human administration. Buyer qualification runs at the inquiry stage.
Specifications
Documentation available on request
Product- and strength-matched first-page previews are shown separately from the Batch COA. Contact sales with the report number for the complete high-resolution file.
Third-party testing in Tianjin
Independent HPLC and mass-spectrometry reports from Qorix , the professional, authoritative third-party analytical laboratory at tjqxgd.com, affiliated with the Tianjin International Joint Academy of Biomedicine.
Regulatory note
Because Thymalin (a multi-peptide extract) and Thymulin (a defined nonapeptide) carry different compositional standards, the two are distinct products and are not chemically interchangeable. At order placement, specify which one is required, and before use confirm the exact identity via the batch COA.
Selected literature
Frequently asked questions
The two forms demand different analytical logic. Thymulin is a defined nonapeptide (CAS 63958-90-7), so its certificate reads like any single-molecule reference standard: HPLC purity, a mass-spec identity value, and water content against a known structure. Thymalin is a bovine-thymus extract with no single-molecule identity, so its certificate cannot report one purity figure; instead it documents an HPLC compositional fingerprint matched to a reference profile, with microbial and endotoxin specifications available on request. The COA names which form the vial represents, so a lab never applies single-peptide acceptance criteria to a multi-component extract.
Thymulin is described as a zinc-binding nonapeptide, so its coordination state is part of its identity and its solution behaviour, and the reference-standard workflow treats the certified form as the defined article rather than assuming free peptide. Because it is a single defined molecule made by routine SPPS, its release documentation supports reproducible structure-activity work, whereas the extract form cannot. Confirm at receipt that the COA identifies the vial as the synthetic nonapeptide with its own CAS before applying single-peptide concentration and purity assumptions to any downstream assay.
Related peptides
