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Khavinson immune / endocrine short-peptide bioregulator
Research documentation
Ask sales for the Crystagen batch COA and the analytical evidence needed to qualify the material for your study. Confirm the available purity and identity records, lot continuity, handling information, and method requirements before ordering.
Overview
Crystagen sits within the Khavinson short-peptide bioregulator framework as its immune- and endocrine-oriented member, hypothesized to act on thymic and endocrine-tissue gene-expression programs under the class's shared premise of tissue-specific bioregulation. Rather than substituting for the better-characterized immune peptides already in the catalog — Thymosin Alpha-1 and Thymulin — it fills the Khavinson-specific niche, aimed at buyers investigating that framework's tissue-targeting hypothesis rather than broader thymic-peptide pharmacology. Lyochem stocks Crystagen in a lyophilized 20 mg vial, released to a ≥99.0% HPLC purity specification. For this class the decisive analytical step is identity confirmation by MS on the batch COA, with sequence confirmation available on request: CAS registration is inconsistent across the family, whose members are distinguished by proposed tissue specificity rather than by any separating analytical fingerprint. Investigators should therefore reconcile the COA identity against their reference protocol at batch receipt before use.
Applications & buyer fit
Khavinson short bioregulators — Adamax, Cortagen, Cartalax, Cardiogen, Bronchogen, Crystagen, Prostamax, Vesugen — ship to research labs replicating Russian-school protocols or running comparative tissue-specific peptide-bioregulator studies. The published literature base for this class is concentrated in Russian-language sources; buyers should expect to consult that literature directly for protocol selection. Analytical-packet expectations are the same as any other lyophilised research peptide.
Academic Laboratories
Universities, medical schools, and government research institutes qualifying a reference standard for a method-development or in vivo workflow.
Every lot has its own batch-specific CoA — HPLC purity and MS identity, plus any analytical scope agreed at quote stage — tied to the exact lot you receive.
Review a representative batch CoA before you order, so you can confirm the packet matches what your method or sponsor audit needs.
Supplied strictly as a research reagent to research institutions — not a finished dosage form and not for human administration. Buyer qualification runs at the inquiry stage.
Specifications
Documentation available on request
Regulatory note
Khavinson bioregulator; CAS commonly not registered. Confirm sequence and identity per batch COA.
Selected literature
Frequently asked questions
The three demand different characterization because they are not the same kind of substance. Thymulin is a defined nine-residue zinc-binding peptide, so a single RP-HPLC peak plus a matching intact mass on ESI-MS, ideally with the metal-binding form noted, confirms it. Crystagen, a defined short peptide, is likewise verified by single-peak purity and an intact mass. Thymalin is a multi-peptide bovine-thymus extract, so like other hydrolysates its identity rests on an HPLC fingerprint against a reference rather than one mass. The certificate must state which compositional class the released lot represents.
For use as a comparator in T-cell or lymphocyte-proliferation work, the paperwork needs to establish both what the molecule is and how much active peptide each vial holds. That means an intact mass from ESI-MS or LC-MS confirming the stated sequence, a RP-HPLC purity value with the method noted, and the counter-ion salt form plus residual-water content so the net-peptide mass, not the gross fill, sets your dosing concentration. Because Crystagen is a synthetic short peptide rather than a tissue extract, a single dominant chromatographic peak is the expected identity signature and should appear on the record.
Related peptides
Thymic immune-modulation peptide(s)
4-mer
Khavinson cortical bioregulator tetrapeptide (Ala-Glu-Asp-Pro, AEDP)