We report net peptide content, not just purity — so the milligrams you dose aren't padded with water and counter-ion. RP-HPLC purity and ESI-MS identity, on a lot-numbered COA.
Net peptide content, not just purity — RP-HPLC + ESI-MS, lot-numbered COA.
Net peptide content on every lot's COA.
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Growth-hormone-releasing peptide-2 · Pralmorelin
Lyochem primary owner
This Lyochem page is the primary SEO owner for research labs, CROs, and method-development teams qualifying GHRP-2 as a documented research-standard lot. The page should answer whether the buyer can review HPLC purity, identity confirmation, lot continuity, stability handling, and assay-fit documentation before ordering.
Overview
GHRP-2 (Pralmorelin) is a synthetic hexapeptide, D-Ala-D-2-Nal-Ala-Trp-D-Phe-Lys-NH2, that agonizes the growth-hormone secretagogue receptor (GHSR/ghrelin receptor) within the GHRP family. It elicits pronounced GH release and has a clinical history as a diagnostic probe of GH-secretory capacity, notably in Japan under the Pralmorelin name. Relative to Ipamorelin — the GH-selective family member — GHRP-2 carries broader receptor activity that also raises cortisol and prolactin at higher doses; the practical trade-off is somewhat greater GH-release magnitude against reduced receptor cleanliness. Lyochem supplies GHRP-2 (Pralmorelin) as a lyophilized reference standard at ≥99.0% HPLC purity, with release resting on RP-HPLC peak integration and mass-spec identity confirmation of this straightforward hexapeptide. Stocked fill sizes are 5 mg and 10 mg to suit common research scales. Choice between family members follows the experimental priority: where avoiding cortisol-axis confounders and preserving GH selectivity is paramount, Ipamorelin is the better fit, whereas GHRP-2 is the standard when peak GH-release magnitude outweighs selectivity.
Applications & buyer fit
GH-axis peptides ship to research labs studying somatotropic-pathway pharmacology, IGF-axis signalling, and pulse vs. sustained-elevation GH biology. Buyers qualifying a new source typically request sequence verification on the first lot, the counter-ion form (acetate by default), and stability data at −20 °C. Blends — the CJC-1295 + Ipamorelin co-formulated lot is the canonical example — are co-lyophilised rather than solution-mixed so the ratio is locked at the lyophilisation step.
Academic Laboratories
Universities, medical schools, and government research institutes qualifying a reference standard for a method-development or in vivo workflow.
Every release ships with its own batch-specific CoA — identity, purity, and the analytical scope agreed at quote stage, tied to the exact lot you receive.
Review a representative batch CoA before you order, so you can confirm the packet matches what your method or sponsor audit needs.
Supplied strictly as a research reagent to research institutions — not a finished dosage form and not for human administration. Buyer qualification runs at the inquiry stage.
Specifications
Documentation available on request
Regulatory note
Sold for Research Use Only under the receiving laboratory's institutional and jurisdictional regulations. Not a finished dosage form, not labelled for human administration — Lyochem's GH-axis lots are scoped to research workflows only. Buyers studying somatotropic pharmacology should specify the counter-ion form (acetate by default) and any pulse-vs-sustained study design notes at quote stage.
Selected literature
Frequently asked questions
GHRP-2 is a synthetic hexapeptide, so the core panel is RP-HPLC for chromatographic purity and ESI-MS for the expected monoisotopic mass, ideally supported by LC-MS/MS fragment confirmation of the sequence. Because the peptide is supplied as a salt (commonly acetate or TFA), a meaningful mass balance also requires counter-ion and residual-water accounting: net peptide content by the COA is lower than gross vial weight once salt and moisture are subtracted. Buyers preparing quantitative research stocks should dose against the net peptide content, not the labeled fill mass, and reference the counter-ion identity on the certificate.
Qualification starts with matching the released-batch mass spectrum against the expected value for GHRP-2 and confirming a single dominant RP-HPLC peak at the specified retention time, ruling out truncation or deletion sequences that a receptor-binding readout would otherwise obscure. Because GHRP-2 (Pralmorelin) is a well-defined molecule, an orthogonal LC-MS/MS sequence check is the strongest identity anchor for a first-time supplier. Record the net peptide content so molar concentrations in GHSR agonist assays are accurate, and store single-use aliquots frozen to protect the reference stock from freeze-thaw-driven potency loss between experiments.