If a supplied lot fails agreed specifications, we’ll replace it at no cost or refund its purchase price in full.
Quality test failed? Free replacement or full refund.
Off-spec? Free replacement or full refund.
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Reference standard · Research use only
GLP-1 / glucagon dual agonist · metabolic research peptide (BI 456906)
Price, MOQ and lead time come in your written quote — usually within 24 hours. No account needed.
Compound facts
| Name | Survodutide |
|---|---|
| CAS number | 2805997-46-8 |
| PubChem CID | 168429725 |
| Molecular formula | C192H289N47O61 |
| Molecular weight | 4231.69 g/mol |
| Appearance | White lyophilized powder |
| Purity specification (HPLC) | ≥ 99.0% |
| On every batch COA | RP-HPLC purity · ESI-MS identity · Bacterial endotoxin · Fill amount (content per vial) |
| On request | LC-MS/MS sequence confirmation · Net peptide content · Water content (Karl Fischer) · Counter-ion content (e.g. acetate, TFA) · Microbial limits |
| Storage | 2–8°C, protect from light |
| Strengths per vial | 10 mg |
| Pack | 10 vials per kit |
| MOQ | On request |
| Lead time | 14–21 days |
| Use | Research use only — not for human or veterinary use |
Identity data from the Lyochem product catalogue, checked against PubChem and registry records. The batch COA of your lot is the record for that lot's results. How to verify a COA
Lot documentation
Values belong to the lot. Ask for the COA of the offered lot before you order.
Independent test fails? Full refund. How it works
Overview
Survodutide (development code BI 456906) is an investigational dual GLP-1 / glucagon receptor co-agonist. Like Mazdutide it engages the GLP-1 and glucagon arms and omits GIP, which places both molecules in the same receptor-coverage bracket — distinct from the GIP-containing dual and tri-agonist peptides — and makes Survodutide a reference tool for glucagon-pathway pharmacology studied alongside the GLP-1 axis. As an investigational compound it is not an approved finished drug; the material supplied here is a research reagent only. Lyochem supplies Survodutide as an analytical reference standard, and every lot has its own batch COA. Because the structure is close enough to other GLP-1 / glucagon dual agonists that catalog-level confusion is possible, the COA leads with ESI-MS identity confirmation alongside RP-HPLC purity (gradient method, UV 214 nm), with counter-ion content and Karl Fischer water content available on request; LC-MS/MS sequence verification is available when required by the buyer’s written analytical scope. The commonly cited CAS should be confirmed against the lot COA. Fills run mg-scale for reproducible aliquoting; this is reference-grade research material, distinct from compounding-scale API supply.
Applications & buyer fit
GLP-1 and metabolic-peptide buyers run incretin-pathway and related research. Ask sales for the COA matched to the offered or supplied lot. If the buyer's written procedure requires tandem-MS sequence evidence or other expanded methods, agree the analytical scope, timing, and cost before quotation.
Academic Laboratories
Universities, medical schools, and government research institutes qualifying a reference standard for a method-development or in vivo workflow.
Biotech R&D Groups
Preclinical biotech and pharmaceutical discovery teams sourcing characterized peptides for receptor-pharmacology, screening, and method-development campaigns.
Every lot has its own batch-specific CoA — RP-HPLC purity, ESI-MS identity, bacterial endotoxin and fill amount, plus any analytical scope agreed at quote stage — tied to the exact lot you receive.
Review a representative batch CoA before you order, so you can confirm the packet matches what your method or sponsor audit needs.
Supplied strictly as a research reagent to research institutions — not a finished dosage form and not for human administration. Buyer qualification runs at the inquiry stage.
Regulatory note
Investigational compound in clinical development; not approved as a finished drug at the time of writing. Sold for Research Use Only under the receiving laboratory's institutional and jurisdictional regulations — not a finished dosage form and not labelled for human administration. CAS is commonly cited but should be verified per batch COA. Buyers are responsible for institutional biosafety review and verifying import eligibility in the destination market.
Selected literature
Frequently asked questions
Both are dual GLP-1 / glucagon co-agonists with no GIP arm, so at the receptor-coverage level they share a bracket; they differ in peptide sequence and lipidation chemistry, and they trace to different clinical-development programs. For reference-standard selection the practical driver is matching the molecule to the data set a study cites. Confirm exact identity per batch COA before treating the two as interchangeable.
Several GLP-1 / glucagon dual agonists are structurally similar enough that a catalog listing alone is not a reliable identity statement. Leading with ESI-MS against the theoretical mass for the supplied form — reproduced on the COA — gives a lab a citable, batch-level identity check, with LC-MS/MS sequence verification available on request for first-time qualification.
Ask sales for the batch COA matched to the offered or supplied lot. Every released lot comes with its batch COA reporting RP-HPLC purity (gradient method, 214 nm) and ESI-MS identity against the theoretical mass for the supplied form, with the chromatogram and mass-spec values reproduced for direct citation; counter-ion content and Karl Fischer water content are available on request. LC-MS/MS sequence verification and bacterial endotoxin (LAL) are on-request add-ons for first-time qualification and in vivo work respectively.
Send any vial from your order to an independent laboratory of your choice. If the report shows the product does not meet the specification on its COA — purity below the stated minimum, or an identity that does not match — share the report with our sales team and we refund that product in full.
Related peptides
GLP-1 / glucagon dual agonist · metabolic research peptide (IBI362 / LY3305677)
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GIP / GLP-1 / glucagon tri-agonist · 39-mer metabolic research peptide
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