If a supplied lot fails agreed specifications, we’ll replace it at no cost or refund its purchase price in full.
Quality test failed? Free replacement or full refund.
Off-spec? Free replacement or full refund.
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Reference standard · Research use only
GIP / GLP-1 dual receptor agonist · 39-mer metabolic research peptide
Price, MOQ and lead time come in your written quote — usually within 24 hours. No account needed.
Compound facts
| Name | Tirzepatide |
|---|---|
| CAS number | 2023788-19-2 |
| PubChem CID | 166567236 |
| Molecular formula | C225H348N48O68 |
| Molecular weight | 4813.45 g/mol |
| Appearance | White to off-white lyophilized powder |
| Purity specification (HPLC) | ≥ 99.0% |
| On every batch COA | RP-HPLC purity · ESI-MS identity · Bacterial endotoxin · Fill amount (content per vial) |
| On request | LC-MS/MS sequence confirmation · Net peptide content · Water content (Karl Fischer) · Counter-ion content (e.g. acetate, TFA) · Microbial limits |
| Storage | 2–8°C, protect from light |
| Strengths per vial | 2 mg · 5 mg · 10 mg · 15 mg · 20 mg · 30 mg · 40 mg · 50 mg · 60 mg · 75 mg · 80 mg · 90 mg · 100 mg · 120 mg |
| Pack | 10 vials per kit |
| MOQ | On request |
| Lead time | 10–18 days |
| Use | Research use only — not for human or veterinary use |
Identity data from the Lyochem product catalogue, checked against PubChem and registry records. The batch COA of your lot is the record for that lot's results. How to verify a COA
Lot documentation
Values belong to the lot. Ask for the COA of the offered lot before you order.
Independent test fails? Full refund. How it works
Overview
Lyochem supplies Tirzepatide as an analytical reference standard, with RP-HPLC purity and MS identity on every batch COA, for incretin-pharmacology research. The molecule is a 39-residue synthetic peptide carrying a C20 fatty-diacid substituent on a lysine side chain; that lipidation governs the reversible albumin binding and the long circulating half-life that set it apart from the GLP-1 mono-agonist series. Functionally it behaves as a balanced co-agonist at both the GIP (glucose-dependent insulinotropic polypeptide) and GLP-1 receptors, which is why the metabolic-research literature treats it as the reference dual-incretin entity. It is the active ingredient of approved finished drugs marketed under separate names, but the material here is characterized and labelled strictly as a research reagent — not a dosage form. The offered or supplied lot is documented by its own batch COA, which reports RP-HPLC purity (gradient method, UV 214 nm) and ESI-MS identity within 0.5 Da of the theoretical 4813.45 g/mol. Sequence confirmation by LC-MS/MS, counter-ion content, peptide content (% net peptide), and water content by Karl Fischer are available on request and listed on the COA when tested. Because the deletion sequences from a 39-mer SPPS run co-elute closely and are not separable by intact mass alone, the tandem-MS b/y-ion ladder is the test that demonstrates sequence identity, and Lyochem can include it when required by the buyer’s written analytical scope. Bacterial endotoxin (LAL) is an on-request add-on for in vivo metabolic-model work. Fills run mg-scale for reproducible aliquoting across a study series; this is reference-grade research material, distinct from compounding-scale API supply.
Applications & buyer fit
GLP-1 and metabolic-peptide buyers run incretin-pathway and related research. Ask sales for the COA matched to the offered or supplied lot. If the buyer's written procedure requires tandem-MS sequence evidence or other expanded methods, agree the analytical scope, timing, and cost before quotation.
Academic Laboratories
Universities, medical schools, and government research institutes qualifying a reference standard for a method-development or in vivo workflow.
Biotech R&D Groups
Preclinical biotech and pharmaceutical discovery teams sourcing characterized peptides for receptor-pharmacology, screening, and method-development campaigns.
Every lot has its own batch-specific CoA — RP-HPLC purity, ESI-MS identity, bacterial endotoxin and fill amount, plus any analytical scope agreed at quote stage — tied to the exact lot you receive.
Review a representative batch CoA before you order, so you can confirm the packet matches what your method or sponsor audit needs.
Supplied strictly as a research reagent to research institutions — not a finished dosage form and not for human administration. Buyer qualification runs at the inquiry stage.
Other formats
Tirzepatide is also kept as a solution in nasal spray bottles.
| Contents | 5 mg, 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg |
|---|---|
| Fill volume | 10 mL or 20 mL |
| Minimum | 10 bottles per content and volume |
| Stock | Held in the United States, shipped within the US |
Regulatory note
Sold for Research Use Only under the receiving laboratory's institutional and jurisdictional regulations. Not a finished dosage form and not labelled for human administration. Tirzepatide is the active ingredient of approved finished drugs under separate brand names, but the bulk active supplied here is a research reagent; buyers are responsible for institutional biosafety review and verifying import eligibility in the destination market.
Selected literature
Frequently asked questions
Tirzepatide CAS is 2023788-19-2; molecular formula C225H348N48O68; average molecular weight 4813.45 g/mol. It is a 39-amino-acid synthetic peptide carrying a C20 fatty-diacid albumin-binding moiety on a lysine side chain. Ask sales for the applicable batch COA; it records the identity method and result actually completed for that lot.
Mass spec alone confirms the intact mass but cannot separate a correctly-synthesized 39-mer from closely-related deletion or aspartimide by-products that co-elute on RP-HPLC. Lyochem confirms identity with RP-HPLC purity (gradient method, 214 nm) and ESI-MS within 0.5 Da of 4813.45 g/mol on the batch COA, with sequence verification by LC-MS/MS (b/y-ion ladder) available on request. If the buyer’s written procedure requires tandem-MS sequence evidence, agree that method and reporting scope before quotation.
Both are once-weekly fatty-acid-conjugated incretin-pathway peptides, but the receptor profile differs: Semaglutide is a selective GLP-1 mono-agonist (31 amino acids, C18 fatty-diacid), while Tirzepatide is a balanced GIP / GLP-1 dual agonist (39 amino acids, C20 fatty-diacid). In published metabolic-research readouts the dual-incretin mechanism produces larger effects on glucose handling and body composition than the GLP-1 mono-agonist class at comparable exposures, which is the reason it is a frequent comparator in incretin-pharmacology studies.
Lyochem supplies Tirzepatide as a reference-grade research reagent, mg-scale, characterized lot-by-lot for reproducible bench and in vivo metabolic research and labelled strictly Research Use Only. That is a different scope from compounding-grade or kg-scale API supply intended for finished-dose preparation. Buyers whose workflow is pharmacy-compounding rather than research should source through a supplier scoped to that use; Lyochem's lots are scoped to the research-documentation chain that a lab needs to cite in a paper: a batch COA with HPLC trace and mass spec, plus sequence verification and stability data on request.
Yes: 5 mg, 10 mg, 15 mg, 20 mg, 30 mg, 40 mg, 50 mg, 60 mg, in 10 mL or 20 mL bottles, minimum 10 bottles per content and volume. This format is held in the United States and shipped within the US; contact sales for availability and a quotation.
Send any vial from your order to an independent laboratory of your choice. If the report shows the product does not meet the specification on its COA — purity below the stated minimum, or an identity that does not match — share the report with our sales team and we refund that product in full.
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