We report net peptide content, not just purity — so the milligrams you dose aren't padded with water and counter-ion. RP-HPLC purity and ESI-MS identity, on a lot-numbered COA.
Net peptide content, not just purity — RP-HPLC + ESI-MS, lot-numbered COA.
Net peptide content on every lot's COA.
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Ala-His-Lys copper(II) chelate; metallotripeptide reference standard
Overview
AHK-Cu is a copper-binding tripeptide reference standard in which alanyl-histidyl-lysine (Ala-His-Lys) chelates a divalent copper ion to form a defined metallopeptide; it belongs to the same copper-tripeptide class as GHK-Cu but carries an alanine rather than a glycine at position one. It is studied in tissue-repair and hair-follicle research contexts. Lyochem supplies AHK-Cu as a lyophilized reference standard characterised by reversed-phase HPLC for peptide purity, ESI-MS for the intact metallopeptide mass, and ICP-MS or a colorimetric assay for copper stoichiometry, confirming the copper is coordinated rather than merely co-present. Each lot ships with counter-ion and water-content data.
Applications & buyer fit
Repair peptides — BPC-157, TB-500, B7-33, PEG-MGF — ship primarily to research labs studying tissue-repair, gastrointestinal-mucosa, tendon-ligament, and vascular-endothelial models. The synthesis itself is reliable, but analytical confirmation is where suppliers differ: buyers qualifying a new source should request sequence verification by tandem MS on the first lot and compare against the labelled sequence directly.
Academic Laboratories
Universities, medical schools, and government research institutes qualifying a reference standard for a method-development or in vivo workflow.
Biotech R&D Groups
Preclinical biotech and pharmaceutical discovery teams sourcing characterized peptides for receptor-pharmacology, screening, and method-development campaigns.
Every release ships with its own batch-specific CoA — identity, purity, and the analytical scope agreed at quote stage, tied to the exact lot you receive.
Review a representative batch CoA before you order, so you can confirm the packet matches what your method or sponsor audit needs.
Supplied strictly as a research reagent to research institutions — not a finished dosage form and not for human administration. Buyer qualification runs at the inquiry stage.
Specifications
Documentation available on request
Regulatory note
Offered by Lyochem solely as an analytical and laboratory research material. This metallopeptide is not supplied for human or veterinary use, for incorporation into consumer or cosmetic products, or for any clinical application.
Selected literature
Frequently asked questions
The two copper tripeptides differ by a single residue (Ala-His-Lys vs Gly-His-Lys), giving a distinct intact mass and RP-HPLC retention. Lyochem confirms identity by ESI-MS against the AHK-Cu mass and by sequence-level LC-MS/MS, so the reference standard is unambiguously the alanine-containing complex.
Copper stoichiometry is measured by ICP-MS or a validated colorimetric copper assay and reported alongside peptide purity, since a copper-tripeptide's identity depends on the metal being coordinated to the peptide. Water content and counter-ion are included on the COA.
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