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Off-spec? Free replacement or full refund.
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Reference standard · Research use only
Reduced glutathione · tripeptide antioxidant reference standard
Price, MOQ and lead time come in your written quote — usually within 24 hours. No account needed.
Compound facts
| Name | Glutathione |
|---|---|
| CAS number | 70-18-8 |
| PubChem CID | 124886 |
| Molecular formula | C10H17N3O6S |
| Molecular weight | 307.32 g/mol |
| Appearance | White to off-white lyophilized powder |
| Purity specification (HPLC) | ≥ 99.0% |
| On every batch COA | RP-HPLC purity · ESI-MS identity · Bacterial endotoxin · Fill amount (content per vial) |
| On request | LC-MS/MS sequence confirmation · Net peptide content · Water content (Karl Fischer) · Counter-ion content (e.g. acetate, TFA) · Microbial limits |
| Storage | 2–8°C, protect from light |
| Strengths per vial | 400 mg · 600 mg · 900 mg · 1000 mg · 1500 mg |
| Pack | 10 vials per kit |
| MOQ | On request |
| Lead time | 7–14 days |
| Use | Research use only — not for human or veterinary use |
Identity data from the Lyochem product catalogue, checked against PubChem and registry records. The batch COA of your lot is the record for that lot's results. How to verify a COA
Lot documentation
Values belong to the lot. Ask for the COA of the offered lot before you order.
Independent test fails? Full refund. How it works
Overview
Glutathione (GSH) is the γ-glutamyl-cysteinyl-glycine tripeptide and the principal intracellular thiol antioxidant in mammalian cells. Its first peptide bond is unusual — formed between the γ-carboxyl of glutamate and the α-amino of cysteine rather than the standard α-α linkage — which makes it resistant to typical peptidases, while the cysteine thiol is the redox-active site that cycles between reduced GSH and oxidized GSSG. It is referenced here as a characterized redox standard, not for any detoxification or pigmentation outcome. Lyochem supplies the reduced GSH form as a reference standard to a ≥99.0% purity specification. The free thiol is the central analytical and stability concern: GSH oxidizes readily to the disulfide-linked GSSG dimer on exposure to air, heat, or light, so the GSH / GSSG ratio is the key freshness marker (target reduced-GSH-dominant); every released lot comes with its batch COA reporting HPLC purity and MS identity, and the GSH / GSSG ratio, residual solvents and water content are available on request and listed on the COA when tested. Storage is at −20 °C, light-protected, and reconstituted material should be used promptly because the reduced form is the labile species. Larger fills are available for assay workflows that consume GSH stoichiometrically. This is reference-grade research material, distinct from compounding-scale API supply.
Applications & buyer fit
Other research peptides in this category — Melanotan I, Melanotan II, PT-141, ACE-031, Adipotide / FTPP, EPO, HMG — ship to research labs studying topics outside the GH / cognitive / immune / mitochondrial / repair / longevity / Khavinson clusters. Each peptide has its own analytical-packet emphasis (e.g. glycoprotein bioassay in IU for HMG; cyclised-form confirmation for oxytocin) noted in the per-product CoA scope.
Academic Laboratories
Universities, medical schools, and government research institutes qualifying a reference standard for a method-development or in vivo workflow.
Biotech R&D Groups
Preclinical biotech and pharmaceutical discovery teams sourcing characterized peptides for receptor-pharmacology, screening, and method-development campaigns.
Every lot has its own batch-specific CoA — RP-HPLC purity, ESI-MS identity, bacterial endotoxin and fill amount, plus any analytical scope agreed at quote stage — tied to the exact lot you receive.
Review a representative batch CoA before you order, so you can confirm the packet matches what your method or sponsor audit needs.
Supplied strictly as a research reagent to research institutions — not a finished dosage form and not for human administration. Buyer qualification runs at the inquiry stage.
Other formats
Glutathione is also kept as a solution in nasal spray bottles.
| Contents | 600 mg |
|---|---|
| Fill volume | 10 mL or 20 mL |
| Minimum | 10 bottles per content and volume |
| Stock | Held in the United States, shipped within the US |
Regulatory note
Lyochem supplies Glutathione strictly for Research Use Only; buyers are responsible for verifying ingredient eligibility in their destination market.
Selected literature
Frequently asked questions
GSH is the reduced form with a free cysteine thiol — the redox-active antioxidant species — while GSSG is the oxidized dimer of two GSH molecules linked by a disulfide. Lyochem supplies the reduced GSH form, but air, heat, and light drive GSH→GSSG oxidation, so the freshness specification is the GSH content as a fraction of total glutathione (reduced-GSH-dominant). A lab whose application is sensitive to the reduced form should first review the GSH / GSSG result on the applicable batch COA; separate confirmation is optional only when required by its written procedure.
At −20 °C, light-protected, with the vial kept sealed; for the most thiol-sensitive work, storing the remainder under inert gas after first use limits further oxidation. Reconstituted solutions should be used promptly because the reduced form is the labile species and oxidizes faster in solution than in the lyophilized state.
GSH is often consumed stoichiometrically rather than catalytically in redox and cell-culture assays, so the working amounts are larger than the µg–mg scales typical of peptide reference standards. The larger fills match that consumption; a lab using small amounts can store the remainder sealed and light-protected at −20 °C to preserve the reduced form.
Yes: 600 mg, in 10 mL or 20 mL bottles, minimum 10 bottles per content and volume. This format is held in the United States and shipped within the US; contact sales for availability and a quotation.
Send any vial from your order to an independent laboratory of your choice. If the report shows the product does not meet the specification on its COA — purity below the stated minimum, or an identity that does not match — share the report with our sales team and we refund that product in full.
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