We report net peptide content, not just purity — so the milligrams you dose aren't padded with water and counter-ion. RP-HPLC purity and ESI-MS identity, on a lot-numbered COA.
Net peptide content, not just purity — RP-HPLC + ESI-MS, lot-numbered COA.
Net peptide content on every lot's COA.
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Acetylated octapeptide; SNAP-25 mimetic, SNARE-assembly inhibitor
Overview
SNAP-8 (acetyl octapeptide-3) is a synthetic eight-residue peptide developed as a topical cosmetic active that lengthens the acetyl-hexapeptide (Argireline) design; its sequence echoes the N-terminal region of the SNAP-25 protein. Research on it centres on competitive interference with SNARE-complex assembly, which dampens neurotransmitter signalling at the neuromuscular junction. Lyochem releases SNAP-8 as a lyophilized reference standard at ≥99.0% HPLC, documented by reversed-phase HPLC purity, ESI-MS confirmation of the acetylated and amidated octapeptide mass, and LC-MS/MS sequence coverage. Counter-ion and water content are reported per lot.
Applications & buyer fit
Other research peptides in this category — Melanotan-1, Melanotan-2, PT-141, ACE-031, Adipotide-FTTP, EPO, HCG, HMG — ship to research labs studying topics outside the GH / cognitive / immune / mitochondrial / repair / longevity / Khavinson clusters. Each peptide has its own analytical-packet emphasis (e.g. glycoprotein bioassay in IU/mg for HCG; cyclised-form confirmation for oxytocin) noted in the per-product CoA scope.
Academic Laboratories
Universities, medical schools, and government research institutes qualifying a reference standard for a method-development or in vivo workflow.
Biotech R&D Groups
Preclinical biotech and pharmaceutical discovery teams sourcing characterized peptides for receptor-pharmacology, screening, and method-development campaigns.
Every release ships with its own batch-specific CoA — identity, purity, and the analytical scope agreed at quote stage, tied to the exact lot you receive.
Review a representative batch CoA before you order, so you can confirm the packet matches what your method or sponsor audit needs.
Supplied strictly as a research reagent to research institutions — not a finished dosage form and not for human administration. Buyer qualification runs at the inquiry stage.
Specifications
Documentation available on request
Regulatory note
This SNAP-8 material is supplied by Lyochem as an analytical reference standard for in-vitro and cosmetic-formulation research only. It is not a drug, is not approved for human or animal use, and must not be applied to the body or used in any clinical procedure.
Selected literature
Frequently asked questions
Lyochem confirms identity by ESI-MS against the SNAP-8 intact mass and by LC-MS/MS sequence coverage of the eight-residue chain, verifying the N-terminal acetylation and C-terminal amidation that define acetyl octapeptide-3. RP-HPLC establishes ≥99.0% main-peak purity.
SNAP-8 is an octapeptide that extends the hexapeptide (Argireline / acetyl hexapeptide-8) design; both are modelled on the N-terminal region of SNAP-25. Lyochem supplies each as a distinct, separately characterised reference standard, with the sequence and intact mass on the COA distinguishing them.
Related peptides
18-mer
Palmitoylated procollagen-fragment pentapeptide (Pal-KTTKS)
16-mer
Copper(II)-binding tripeptide reference standard (Gly-His-Lys · Cu2+)