If a supplied lot fails agreed specifications, we’ll replace it at no cost or refund its purchase price in full.
Quality test failed? Free replacement or full refund.
Off-spec? Free replacement or full refund.
Reading a Peptide HPLC Trace — A 5-Minute Field Guide for Bench Scientists. Read our briefing →
Reading a peptide HPLC trace — a field guide. Read →
On reading HPLC traces. Read →
Reference standard · Research use only
Also known as CagriSema (Cagrilintide + Semaglutide)
Co-characterized amylin + GLP-1 reference pairing
Price, MOQ and lead time come in your written quote — usually within 24 hours. No account needed.
Compound facts
| Name | CagriSema |
|---|---|
| Also known as | CagriSema (Cagrilintide + Semaglutide) |
| CAS number | (blend, components have individual CAS numbers) |
| Purity specification (HPLC) | ≥ 99.0% (component-wise for blends) |
| On every batch COA | RP-HPLC purity · ESI-MS identity · Bacterial endotoxin · Fill amount (content per vial) |
| On request | LC-MS/MS sequence confirmation · Net peptide content · Water content (Karl Fischer) · Counter-ion content (e.g. acetate, TFA) · Microbial limits |
| Storage | 2–8°C, protect from light |
| Strengths per vial | 5 mg · 10 mg · 20 mg |
| Pack | 10 vials per kit |
| MOQ | On request |
| Lead time | 14–21 days |
| Use | Research use only — not for human or veterinary use |
Identity data from the Lyochem product catalogue. The batch COA of your lot is the record for that lot's results. How to verify a COA
Lot documentation
Values belong to the lot. Ask for the COA of the offered lot before you order.
Independent test fails? Full refund. How it works
Overview
CagriSema is the combination of the long-acting amylin analog Cagrilintide with the GLP-1 receptor agonist Semaglutide — two molecules acting through distinct receptor families (the amylin / calcitonin-receptor axis and the GLP-1 receptor) that the metabolic-research literature studies together under the CagriSema designation. As an investigational combination it is not an approved finished drug; the material referenced here is a research reagent only, framed as a reference pairing rather than for any weight-management outcome. Lyochem's methodology preference for a two-component system is to characterize each component on its own analytical packet rather than ship a pre-mixed blend whose per-component data is obscured. Cagrilintide and Semaglutide are each supplied as separately characterized lots — each with its own batch COA reporting RP-HPLC purity (gradient method, UV 214 nm) and ESI-MS identity, with sequence confirmation by LC-MS/MS, counter-ion content and Karl Fischer water content available on request — so a lab can confirm identity and purity of each before preparing the combination in-protocol at its own ratio. Because the components carry individual CAS numbers rather than a single registered identifier for the combination, the per-lot COA is the operative identity document; confirm the API of each component by COA / label before use. Fills run mg-scale; this is reference-grade research material, distinct from compounding-scale API supply.
Applications & buyer fit
GLP-1 and metabolic-peptide buyers run incretin-pathway and related research. Ask sales for the COA matched to the offered or supplied lot. If the buyer's written procedure requires tandem-MS sequence evidence or other expanded methods, agree the analytical scope, timing, and cost before quotation.
Academic Laboratories
Universities, medical schools, and government research institutes qualifying a reference standard for a method-development or in vivo workflow.
Biotech R&D Groups
Preclinical biotech and pharmaceutical discovery teams sourcing characterized peptides for receptor-pharmacology, screening, and method-development campaigns.
Every lot has its own batch-specific CoA — RP-HPLC purity, ESI-MS identity, bacterial endotoxin and fill amount, plus any analytical scope agreed at quote stage — tied to the exact lot you receive.
Review a representative batch CoA before you order, so you can confirm the packet matches what your method or sponsor audit needs.
Supplied strictly as a research reagent to research institutions — not a finished dosage form and not for human administration. Buyer qualification runs at the inquiry stage.
Other formats
CagriSema is also kept as a solution in nasal spray bottles.
| Contents | 10 mg |
|---|---|
| Fill volume | 10 mL or 20 mL |
| Minimum | 10 bottles per content and volume |
| Stock | Held in the United States, shipped within the US |
Regulatory note
Investigational combination; not approved as a finished drug at the time of writing. Components carry individual CAS numbers — confirm each component's API identity by batch COA / label before use. Sold for Research Use Only under the receiving laboratory's institutional and jurisdictional regulations — not a finished dosage form and not labelled for human administration. Buyers are responsible for institutional biosafety review and import-eligibility verification.
Selected literature
Frequently asked questions
No. Lyochem supplies Cagrilintide and Semaglutide as separate characterized lots, each with its own analytical packet, rather than a pre-mixed vial. This lets a lab confirm the identity and purity of each component independently before preparing the combination in-protocol — the methodologically cleaner approach, because a pre-mixed product obscures the per-component analytical data a citable methods section needs.
CagriSema is a combination of two distinct molecules, each with its own CAS Registry Number, rather than a single chemical entity, so there is no single registered identifier for the pairing. Identity is established at the component level on the applicable batch COA (ESI-MS against the theoretical mass for each supplied form); buyers should confirm the API of each component by COA or label rather than relying on the combination name.
Each component is supplied as its own lot with its own batch COA — RP-HPLC purity and ESI-MS identity, with LC-MS/MS sequence verification, counter-ion content and Karl Fischer water content available on request — so the pairing is defined by two citable batch COAs rather than a single blended COA. A lab reconstitutes and combines the two at its chosen ratio in-protocol, with each component's identity already confirmed against its own standard.
Yes: 10 mg, in 10 mL or 20 mL bottles, minimum 10 bottles per content and volume. This format is held in the United States and shipped within the US; contact sales for availability and a quotation.
Send any vial from your order to an independent laboratory of your choice. If the report shows the product does not meet the specification on its COA — purity below the stated minimum, or an identity that does not match — share the report with our sales team and we refund that product in full.
Related peptides
Long-acting amylin analog · metabolic research peptide
Also in nasal spray
GLP-1 receptor agonist · 31-mer metabolic research peptide
Also in nasal spray
GIP / GLP-1 dual receptor agonist · 39-mer metabolic research peptide
Also in nasal spray